The MLB best bets for September 25 include the New York Yankees vs. Toronto Blue Jays, Houston Astros vs. Seattle Mariners, and Milwaukee Brewers vs. Pittsburgh Pirates games. The Yankees are favored to win against the Blue Jays, with a moneyline of -155. The Astros are also expected to win against the Mariners, with a moneyline of -182. The Brewers are underdogs against the Pirates, with a moneyline of +110. The total runs for the Yankees vs. Blue Jays game is set at 9.5, while the Astros vs. Mariners and Brewers vs. Pirates games have totals of 9 and 8.5 runs, respectively.
