The Buffalo Bills stunned the NFL world with a 16-14 upset over the Arizona Cardinals in Week 1. Josh Allen threw for 270 yards and a touchdown, while Devin Singletary ran for 75 yards and another score. The Cardinals, led by Kyler Murray’s 308 passing yards and a touchdown, struggled to find the end zone, settling for three field goals. The Bills’ defense came up big in the fourth quarter, forcing a turnover on downs to secure the victory.