The Oakland Athletics take on the Chicago Cubs in MLB action on Wednesday, September 18. According to the latest odds, the Cubs are favored to win at home, with a moneyline of -135. The Athletics are underdogs at +125. The over/under for runs scored is set at 9.5. The Athletics have won three of their last five games, while the Cubs have lost three of their last five. In their last meeting on September 15, the Cubs won 11-3.